Milpro Dogs contains 12,5 mg milbemycin oxime and 125 mg praziquantel per tablet.
DIRECTIONS FOR USE:
Use only as directed.
Only for use by persons authorised thereto in terms the Veterinary and Para-Veterinary Professions Act, 1982 (Act 19 of 1982)
In dogs: The minimum recommended dose rate is 0,5 mg milbemycin oxime and 5 mg praziquantel per kg body mass, administered as a single oral dose. Milpro should be administered with or after food for maximum efficacy.
Adult dogs should be treated 4 times a year.
Depending on the body mass of the dog, practical dosing is as follows:
Body mass dog
Milpro Dogs (dogs more than 5 kg)
5 – 25 kg
1 Tablet
25 – 50 kg
2 Tablets
50 – 75 kg
3 Tablets
EFFICACY:
Milpro has been shown to be highly effective in treating mixed infections of cestodes and nematodes of the following species:
Do not use in puppies younger than 6 weeks of age. Do not use Milpro Dogs in dogs with a body mass of less than 5 kg.
The margin of safety of Milpro in Collies or related dog breeds is less than in other breeds. As such, the recommended dose should be strictly observed in these breeds.
Echinococcus spp. represents a hazard for humans (zoonosis). If Echinococcus spp. has been detected, specific treatment and follow-up guidelines should be followed, whilst steps should be taken to safe-guard persons.
No studies have been performed in severely debilitated dogs or individuals with seriously compromised kidney or liver function. Milpro is not recommended for such animals and should only be used, following a risk/benefit assessment by the responsible veterinarian. At 10 times and higher dose rates (overdosing), mild transient clinical signs of mydriasis, depression, drooling, paresis, trembling and/or a staggered gait may occur in some dogs. Such symptoms will subside spontaneously within a day. No antidote is known.
Keep out of reach of children, uninformed persons and animals.
Although this remedy has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.
PRECAUTIONS:
The concurrent use of Milpro with the macrocyclic lactone selamectin is well tolerated. No interactions were observed when the recommended dose of selamectin was administered concomitantly with milbemycin oxime and praziquantel combination tablet formulations at the recommended dose. In the absence of studies, caution should be exercised when other macrocyclic lactones are administered concomitantly with Milpro.
Wash hands after use.
Do no contaminate water courses, as milbemycin may be harmful to fish and other aquatic organisms.
First aid: In the event of accidental ingestion of tablets, particularly by a child, seek medical advice immediately and show this package insert to the physician.
Note to physician: Treatment is symptomatic and supportive.
STORAGE INSTRUCTIONS:
Store at or below 30 °C in the original packaging material. After first opening the immediate packaging, the tablets can be stored for 6 months.
PRESENTATION:
Milpro Dogs: Round shaped, beige to pale brown meat film coated flavoured tablets. Blister strips are packed into cardboard cartons containing 48 tablets per carton.
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